5F-AKB-48

$140.00

5F-AKB-48 or 5F-APINACA is a synthetic cannabinoid drug containing a substituted indazole group. This indazole moiety is substituted at R1 with a fluoropentyl chain, a substitution shared with 5F-PB-22. And the indazole is substituted at R3 with a carboxamide group. This group is N-substituted at its terminal amine group with an adamantane group. This group consists of four fused cyclohexane rings in a unique structure called a diamondoid. 5F-AKB-48 is an analog of STS-135 in which the core indole structure is substituted with an indazole base

Category: Indazole Based

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5F-AKB-48 (5F-APINACA) – Product Description, Composition, Usage, and Dosage

Product Name: 5F-AKB-48
Also Known As: 5F-APINACA, 5F-AKB48
CAS Number: 1445583-51-6
Molecular Formula: C23H31FN4O
Molecular Weight: 398.52 g/mol
Purity: ≥ 98% (by HPLC)
Form: White crystalline powder
Type: Synthetic cannabinoid
Legal Status: Research chemical only. Not for human or animal consumption.

🔬 Product Description

5F-AKB-48 is a synthetic cannabinoid that belongs to the indazole-based family. It was originally synthesized for scientific and forensic research to study cannabinoid receptor interactions. 5F-AKB-48 mimics the activity of THC by binding to CB1 and CB2 receptors, producing potent cannabinoid-like effects in vitro and in lab models. Due to its high affinity and efficacy at cannabinoid receptors, it is commonly used in pharmacological research and receptor mapping.

🧪 Chemical Composition

Core Structure: Indazole-based synthetic cannabinoid
Key Components:
- Indazole ring
- N-(1-amino-3-methyl-1-oxobutan-2-yl) group
- 5-fluoropentyl side chain

This compound is a fluorinated analog of AKB-48 (APINACA), making it more potent in CB1 receptor activation.

⚗️ Usage

Researchers and analysts strictly use 5F-AKB-48 for research and analytical applications, including but not limited to:

Receptor binding assays
Neuropharmacological studies
Structure-activity relationship (SAR) analysis
Forensic toxicology research
Academic laboratory testing

Note: This product is not approved for human or veterinary use. Improper handling may result in health risks.

🧴 Dosage and Handling

Experts have not officially recommended a dosage, since it does not serve clinical purposes. However, in controlled lab experiments:

Concentration Range: 1 µM to 10 µM is commonly used in receptor-binding assays.
Always dilute using analytical-grade solvents.
Use appropriate protective equipment (PPE), including gloves, eye protection, and lab coat.
Store in a cool, dry place away from light and moisture.

⚠️ Legal & Safety Disclaimer

This product is sold strictly for laboratory research purposes.
Not for ingestion, inhalation, injection, or topical use.
Buyer must be over 18 years old and qualified to handle research chemicals.
Ensure compliance with your local, state, and federal regulations before purchasing or using.

📦 Packaging and Shipping

Secure, discreet, and professionally sealed
Available in quantities from 100 mg to 5 g
Custom COAs (Certificate of Analysis) available on request

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