5Fur-144 (5″-fluоrо-UR-144) іѕ a drug that асtѕ аѕ a potent аgоnіѕt fоr thе саnnаbіnоіd rесерtоrѕ CB1 аnd CB2 wіth EC50 vаluеѕ оf 98 nM аnd 83 nM, rеѕресtіvеlу. Visit to Order It іѕ a 3-(tetramethylcyclopropylmethanoyl)indole dеrіvаtіvе rеlаtеd to соmроundѕ such as UR-144, A-796,260 аnd A-834,735, but іt is nоt specifically lіѕtеd іn thе patent оr ѕсіеntіfіс lіtеrаturе аlоngѕіdе thеѕе оthеr similar compounds, and appears to hаvе not previously bееn mаdе bу Abbоtt Laboratories, dеѕріtе fаllіng wіthіn the claims оf раtеnt WO 2006/069196. XLR-11 wаѕ fоund tо produce rapid, short-lived hуроthеrmіс effects in rаtѕ аt doses оf 3 mg/kg аnd 10 mg/kg, suggesting that іt is оf соmраrаblе роtеnсу tо APICA аnd STS-135.
Researchers have identified 5FUR-144, also known as XLR-11 or 5-fluoro UR-144, as a synthetic cannabinoid in various herbal incense products. It acts as a potent agonist for the cannabinoid receptors CB1 and CB2, with EC50 values of 98 nM and 83 nM, respectively. citeturn0search4
Chemical Composition and Structure
The chemical name for 5FUR-144 is 1-(5-fluoropentyl)-1H-indol-3-ylmethanone. Its molecular formula is C21H28FNO, resulting in a molecular weight of 329.45 g/mol. The structure comprises an indole core linked to a tetramethylcyclopropyl group via a methanone bridge, with a fluorinated pentyl chain at the nitrogen atom of the indole ring.
Physical and Chemical Properties
- Boiling Point: Predicted to be approximately 442.0±25.0 °C.
- Density: Estimated at 1.08±0.1 g/cm³.
- Storage Conditions: Recommended to be stored at -20°C to maintain stability.
Description and Usage
Scientists developed 5FUR-144, an aminoalkylindole compound, to mimic cannabinoid (CB) activity. Drug traffickers later incorporated it into herbal incense products, which authorities have seized.
Its inclusion in these products suggests its potential for recreational use, likely due to its psychoactive effects.
Safety and Legal Status
Researchers have not thoroughly documented the safety profile of 5FUR-144. However, health experts have linked synthetic cannabinoids, in general, to adverse effects, including acute kidney injury Due to health concerns, 5FUR-144 has been subject to legal restrictions in various jurisdictions. For instance, the U.S. Drug Enforcement Administration (DEA) classified it as a Schedule I controlled substance in 2013, indicating no accepted medical use and a high potential for abuse.
Conclusion
5FUR-144 is a synthetic cannabinoid with a specific chemical structure and properties that have led to its use in certain herbal incense products. While it has applications in research, its potential for abuse and associated health risks have prompted legal controls in several regions. Further studies are necessary to fully understand its pharmacological effects and safety profile.
5Fur-144 for sale online is a psychoactive drug that acts as an agonist with the cannabinoid receptors. It binds itself with the cannabinoid receptors. 5fur-144 for sale online is a stimulant or a hallucinogen substance that was unknown to many people. It had not been used for many scientific experiments either. However, it gained popularity since its discovery in 2012. 5Fur-144 for sale online.


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