Information on How to Buy 5-MeO-pyr-T 

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5-MeO-pyr-T, or 5-methoxy-N,N-tetramethylenetryptamine, is a lesser-known psychedelic compound belonging to the tryptamine class. It is structurally characterized as the 5-methoxy analog of pyr-T. The synthesis of 5-MeO-pyr-T was first reported by researchers Hunt and Brimblecombe, who acknowledged S. Mitzal for the characterization of its chemical properties.

Chemical Structure and Properties

The chemical formula of 5-MeO-pyr-T is C₁₅H₂₀N₂O, resulting in a molecular mass of 244.34 g/mol. It typically appears as an off-white oil with a density of 200.3 g/cm³. The compound’s melting point ranges between 164 to 167 °C, specifically for its hydrochloride salt form, while the freebase form has a boiling point between 160 to 170 °C at 0.05 mm/Hg. Other notable properties include a log P value of 2.75270, a refractive index of 1.614, and a vapor pressure of 7.42×10⁻⁷ mm/Hg.

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Pharmacological Profile

Pharmacological studies on 5-MeO-pyr-T are limited. However, it has been identified as an agonist of the 5-HT₇ receptor, with a Kᵢ value of approximately 630.96 nM. This suggests potential serotonergic activity, although comprehensive data on its pharmacodynamics, metabolism, and toxicity remain scarce.

Analogous Compounds

5-MeO-pyr-T is structurally related to several compounds within the tryptamine

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Testing was performed on rats using this compound while characterizing various agonists of the 5-HT₇ receptor. It is an agonist with a K_i value of 630.96nM.

It has been found to act as a partial serotonin releasing agent.

Very little other data exists about the pharmacological properties, metabolism, and toxicity of 5-MeO-pyr-T.

• Pyr-T
• 4-F-5-MeO-pyr-T
• Tryptamine
• Psychedelics, dissociatives and deliriants

5-MeO-pyr-T (5-methoxy-N,N-tetramethylenetryptamine) is a lesser-known psychedelic drug. It is the 5-methoxy analog of pyr-T. 5-MeO-pyr-T was first synthesized by Hunt & Brimblecombe, who credited S. Mitzal for characterization of chemical properties. Later human tests were reported by Alexander Shulgin, in his book TiHKAL. An oral dosage of 0.5 to 2 mg, and an inhaled dosage of 2–3 mg are reported. 5-MeO-pyr-T causes varying reactions, such as amnesia, tinnitus, vomiting, and a 5-MeO-DMT-like rushing sensation. At the highest dosage reported in TiHKAL, the subject describes awakening from an apparent fugue state during which they were wandering the streets, with complete amnesia upon awakening.