Buy 3-Meo-PcP Online

Buy 3-MeO-PCP ,3-Methoxyphencyclidine (3-MeO) is a lesser-known novel dissociative substance of the arylcyclohexylamine class that produces dissociative, anesthetic, and hallucinogenic effects when administered. It is structurally related to arylcyclohexylamines like PCP, MXE, and 3-MeO-PCP for sale online 3 Meo PcP .

About

3 Meo Pce for sale online,it was first synthesized in 1979 to investigate the structure-activity relationship of phencyclidine (PCP) derivatives. Its activity in humans was not described until 1999 when a chemist using the pseudonym John Q. Beagle reported qualitative similarities to PCP along with comparable potency. To Buy 3-MeO-PCP Visit

3-MeO-PCP: Chemical Composition, Properties, and Pharmacology

Introduction

3-Methoxyphencyclidine (3-MeO-PCP) is a dissociative anesthetic and research chemical that belongs to the arylcyclohexylamine class. It is chemically related to phencyclidine (PCP) and ketamine and is known for its NMDA receptor antagonism, leading to dissociative and psychoactive effects. Since its emergence in the 2010s, it has been investigated for its potential effects on perception, cognition, and consciousness.

Chemical Composition and Structure

• IUPAC Name: 1-[1-(3-Methoxyphenyl)cyclohexyl]piperidine

• Molecular Formula: C18H27NO

• Molecular Weight: 273.41 g/mol

• Structure: It consists of a cyclohexyl ring attached to a piperidine moiety, with a methoxy (-OCH₃) group on the benzene ring.

Ingredients and Synthesis

The synthesis of this chemical involves multiple chemical steps, including:

1. Precursors: Typically, a benzyl cyanide derivative and a cyclohexanone derivative serve as starting materials.

2. Reagents and Catalysts: Commonly used reagents include lithium aluminum hydride (LAH) for reduction and methanol for methylation of the aromatic ring.

3. Final Steps: The reaction proceeds through a Grignard or reductive amination approach to form the final piperidine structure.

Due to its complex synthesis, it requires expertise in organic chemistry and is not produced through simple extraction methods.

Physical and Chemical Properties

• Appearance: Off-white to light tan crystalline powder

• Solubility: Soluble in organic solvents like ethanol and dimethyl sulfoxide (DMSO); limited solubility in water

• Melting Point: Approx. 250-260°C

• Boiling Point: Not well-documented due to decomposition at high temperatures

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Pharmacology and Mechanism of Action

This Chemical primarily acts as:

1. NMDA Receptor Antagonist: It blocks NMDA receptors, reducing excitatory neurotransmission, leading to anesthetic and dissociative effects.

2. Dopaminergic and Serotonergic Modulation: Unlike PCP, It has mild stimulant-like properties, potentially influencing dopamine and serotonin systems.

3. Sigma Receptor Affinity: It may have additional interactions with sigma receptors, contributing to its psychoactive profile.

Effects and Potential Uses

Subjective and Neurological Effects

• Dissociation: Users report feelings of detachment from reality and sensory alterations.

• Cognitive Modulation: Effects range from mild stimulation to confusion, depending on dosage.

• Anesthetic and Analgesic Properties: Similar to ketamine, but longer-lasting and with a different psychoactive profile.

Potential Medical and Research Applications

• Neuroscientific Research: Studied for its role in understanding NMDA receptor function.

• Pain Management: Limited exploration as an analgesic alternative to ketamine.

• Psychiatric Implications: Investigated for potential antidepressant properties, though not clinically approved.

Specifications and Safety Considerations

• Purity: Generally tested using techniques like gas chromatography-mass spectrometry (GC-MS) or nuclear magnetic resonance (NMR) spectroscopy.

• Dosage and Toxicity:

  • Threshold effects reported at 3-5 mg

  • Common dosages range from 5-15 mg

  • Higher doses (>20 mg) may lead to severe dissociation and neurotoxicity

• Adverse Effects: Confusion, motor impairment, tachycardia, hypertension, and potential risk of psychosis at high doses.

Legal Status

3-MeO-PCP is classified as a controlled substance in many countries, including the UK and parts of Europe. In the United States, its status remains ambiguous under analog laws.

Conclusion

3-MeO-PCP is a potent dissociative compound with pharmacological similarities to PCP and ketamine. While it has research value, its psychoactive nature and potential for misuse raise safety and legal concerns. Further studies are needed to explore its therapeutic potential while mitigating risks.